早期发病的 菌体 spp. 移植脏后的感染:系统性审查
Carlo Galdino Riva1, Roberto Cacciola2, Giulia Cusumano1
1General Surgery and Kidney Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Clinical transplantation
|September 24, 2025
概括
质菌感染 (MIs) 在移植 (KT) 接受者中越来越常见,导致严重的并发症. 本综述强调了它们的流行病学,临床特征和治疗方法,强调了对实体器官移植患者进行进一步研究的必要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 移植免疫学 移植免疫学
背景情况:
- 菌体 spp. 菌体 spp. 在 感染 (MIs) 在移植 (KT) 接受者中正在增加.
- 这些感染带来严重并发症和移植失败的风险.
- 关于KT患者中MIs的特定流行病学,临床表现,诊断和治疗的数据有限.
研究的目的:
- 系统地审查有关Mycoplasma spp.的现有文献. 移植脏后的感染.
- 巩固有关KT接受者的MI流行病学,临床特征,诊断方法和治疗策略的信息.
主要方法:
- 使用PubMed,Embase,Scopus和Cochrane数据库进行了系统审查.
- 分析了1970年至2023年间发表的病例报告,病例系列和队列研究的数据.
主要成果:
- 该综述分析了不同类型的研究中30次心脏病发作.
- 感染主要影响手术部位 (n=18) 或尿路 (n=6),通常是由Mycoplasma hominis (n=28) 引起的.
- 常见的症状包括发烧,腹痛,白细胞症和CRP升高. 治疗包括四环素或诺,但结果包括移植损失 (n=6) 和死亡 (n=2).
结论:
- 菌体 spp. 菌体 spp. 在 感染在移植受体中是一个重大问题.
- 这些发现强调了需要在固体器官移植的更广泛背景下增加对MI的认识和进一步研究.
相关概念视频
01:26Kidney Transplant II: Surgical Procedure
270
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
270
01:28Kidney Transplant I: Introduction
297
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
297
01:16Kidney Transplant III: Nursing Management
286
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
286
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
267
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
267
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
238
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
238
01:27Acute Pyelonephritis I: Introduction
421
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
421