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Updated: Aug 6, 2026

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鼠标模型和实验协议用于研究抗体介导的移植拒绝

Jason M Zimmerer1, Hatem Aldhahi1, Ginny L Bumgardner1

  • 1Department of Surgery, Comprehensive Transplant Center, and the College of Medicine, The Ohio State University, Columbus, Ohio.

Current protocols
|September 24, 2025
PubMed
概括

抗体介导排斥 (AMR) 仍然是器官移植的一个主要障碍. 本研究详细介绍了使用小鼠模型的方法论,以研究AMR机制,并开发用于移植成功的新疗法.

关键词:
所有的抗体.通过抗体介导的排斥.移植 移植 移植 移植

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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