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相关概念视频

Patch Clamp01:18

Patch Clamp

6.0K
Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
6.0K

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A Microfluidic-based Hydrodynamic Trap for Single Particles
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用声学驱动的微型机器人用于单粒子运输.

Zhikun Miao1, Tao Feng1, An Ren2

  • 1Center for X-Mechanics, Department of Engineering Mechanics, Zhejiang University, Hangzhou 310027, China.

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科学领域:

  • 机器人技术 机器人技术 机器人技术
  • 生物医学工程 生物医学工程
  • 纳米技术纳米技术

背景情况:

  • 声学微机器人对于微物体操纵非常有用.
  • 只有声学驱动的微机器人在协同处理和移动方面面临挑战,通常需要辅助驱动.
  • 现有系统可能需要磁控来帮助完成复杂的任务.

研究的目的:

  • 开发一个声学驱动的微型机器人,用于独立的微型物体紧和移动.
  • 为了能够精确控制微操作任务,使用不同的声频.
  • 为了证明纯粹声学驱动的微机器人在具有挑战性的微观操作中的能力.

主要方法:

  • 开发了一种微型紧机器人,其爪子由声学诱导的二次Bjerknes力驱动,用于紧.
  • 集成的鞭子在声输入下振荡,用于移动.
  • 利用不同的声频来控制紧和运动的独立控制.
  • 经过测试,通过狭窄的通道进行导航,并从集群中选择性地检索颗粒.

主要成果:

  • 微型紧机器人成功地紧并运输了微型物体,包括活细胞,没有损坏.
  • 通过使用不同的声频来实现紧和运动的独立控制.
  • 机器人通过狭窄的道,约为其宽度的2.1倍.
  • 从一个集群中展示了选择性的粒子挑选.

结论:

  • 开发的以声学驱动的微型接机器人为微型物体的运输提供了多功能解决方案.
  • 该系统通过实现协同处理和移动来克服纯声动力微机器人的局限性.
  • 该技术显示出先进的临床疗法和微小手术的巨大潜力.