乳腺癌幸存者的生活目标和死亡率
Juhua Luo1, Stephanie A Hooker2, Candyce H Kroenke3
1Department of Epidemiology and Biostatistics, School of Public Health, Indiana University.
概括
拥有强烈的生活目标 (PIL) 显著降低乳腺癌幸存者的死亡风险. 身体活动和社会参与等关键因素调解了这种积极的生存效应.
科学领域:
- 在瘤学瘤学.
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 生活中的目的 (PIL) 与癌症幸存者的幸福感有关.
- 乳腺癌幸存者的PIL和生存结果之间的关联尚未得到充分证实.
研究的目的:
- 研究乳腺癌幸存者的生命目的 (PIL) 和死亡风险之间的关系.
- 探索潜在的调解途径,如身体活动,压力和社会参与,这些途径将PIL与生存联系起来.
主要方法:
- 对来自"妇女健康倡议"队列的3692名乳腺癌幸存者的分析.
- 2012年使用修改后的Ryff和Keyes规模评估PIL.
- 考克斯的比例危险模型和调解分析,以确定死亡风险和途径.
主要成果:
- 较高的PIL四分位数与33%的死亡风险降低有关 (HR = 0.67).
- 这种联系在70岁以下的女性和在过去一年内被诊断出来的女性中更为强烈.
- 身体活动,低感知压力和社会参与共同解释了51%的PIL死亡率关联.
结论:
- 提高生活目标 (PIL) 与乳腺癌患者的生存率有显著的改善有关.
- 旨在增强PIL,体力活动,减轻压力和社会参与的干预措施可以改善幸存者的结果.
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