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Updated: Jan 17, 2026

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在肺纤维化中,Six1通过调节TP53促进了膜表皮老化,通过调节TP53促进了肺纤维化

Yan Fan1, Zhen Tian1, Hongyan Zheng1

  • 1Department of Respiratory and Critical Care Medicine, National Clinical Research Center of Respiratory Disease, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.

International immunopharmacology
|September 24, 2025
PubMed
概括

鼻眼同源盒1 (Six1) 通过促进肺细胞中的细胞衰老来驱动异常性肺纤维化 (IPF). 向Six1为治疗肺纤维化 (PF) 提供了一个有前途的治疗策略.

关键词:
异形性肺纤维化症 异形性肺纤维化症衰老是一种衰老.阴影眼圈的同源盒同类物 1 1转录因子是一种转录因子.瘤蛋白质p53是什么?第二种类型的膜表皮.

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