Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Formation of the Platelet Plug01:22

Formation of the Platelet Plug

8.7K
The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
8.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Intradural Fibrosis Following Percutaneous Spinal Cord Stimulator Placement: A Case Report.

Pain practice : the official journal of World Institute of Pain·2026
Same author

Outcome of cerebral embolic protection during transcatheter aortic valve replacement in high-risk patient for stroke.

JTCVS structural and endovascular·2026
Same author

Novel application of the NeVa VS device in the management of severe vasospasm after meningitis.

Journal of cerebrovascular and endovascular neurosurgery·2026
Same author

Coronal Spinal Deformity Does Not Predict Clinical Response to Thoracic Spinal Cord Stimulation.

Neuromodulation : journal of the International Neuromodulation Society·2026
Same author

Treatment Durability After Subdural Evacuating Port System, Middle Meningeal Artery Embolization, and Combined Therapy for Chronic Subdural Hematoma.

Neurosurgery·2026
Same author

Evaluation of thoracolumbar spine injury utilizing plain film and physical exam in the pediatric population: A multicenter study.

The journal of trauma and acute care surgery·2026

相关实验视频

Updated: Jan 17, 2026

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.6K

血小板功能测试不能预测轻度创伤性脑损伤的出血进展.

Tessa A Harland1, Andrew Ku2, Gregory Topp1

  • 1Department of Neurosurgery, Albany Medical College, Albany NY, United States.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
|September 24, 2025
PubMed
概括

轻度创伤性脑损伤患者的血小板功能测试没有显示恶化的风险增加. 这些发现表明,目前的指导方针可能需要对抗血小板治疗管理进行重新评估.

关键词:
成年人脑损伤是什么意思抗血小板治疗是一种抗血小板疗法.脑损伤指南 脑损伤指南头部创伤的人.放射性进展的放射性进展创伤性脑损伤是一种创伤性脑损伤.

更多相关视频

Stab-Wound Mouse Model for Studying Hemorrhage and Inflammation in Traumatic Brain Injury
04:03

Stab-Wound Mouse Model for Studying Hemorrhage and Inflammation in Traumatic Brain Injury

Published on: February 21, 2025

995
Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
07:21

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury

Published on: May 27, 2022

3.6K

相关实验视频

Last Updated: Jan 17, 2026

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.6K
Stab-Wound Mouse Model for Studying Hemorrhage and Inflammation in Traumatic Brain Injury
04:03

Stab-Wound Mouse Model for Studying Hemorrhage and Inflammation in Traumatic Brain Injury

Published on: February 21, 2025

995
Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
07:21

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury

Published on: May 27, 2022

3.6K

科学领域:

  • 神经创伤是一种神经创伤.
  • 血液学 血液学 血液学
  • 临床医学 临床医学

背景情况:

  • 抗血小板药物通常被认为会恶化创伤性内出血 (ICH) 的结果.
  • 目前的指导方针建议扩展观察和成像,受这种假设的影响.
  • 然而,抗血小板治疗对血小板功能和ICH临床结果的实际影响尚未完全理解.

研究的目的:

  • 调查治疗性血小板抑制与创伤性ICH患者的X光或临床进展之间的关联.
  • 评估血小板功能测试在治疗轻度创伤性ICH后接受抗血小板治疗的患者的实用性.

主要方法:

  • 对接受抗血小板治疗的轻度创伤性ICH (GCS 13-15) 的成年患者进行了回顾性队列研究.
  • 血小板功能测试 (VerifyNow PRU或PFA) 将患者分类为治疗或非治疗.
  • 用敏感性分析对不同组的放射性进展,手术干预和死亡率进行比较.

主要成果:

  • 在治疗组 (20.4%) 和非治疗组 (16.8%) 之间,放射性进展没有显著差异.
  • 手术干预和死亡率较低,在不同组之间可比.
  • 敏感性分析证实了治疗抑制和不良结果之间缺乏关联.

结论:

  • 治疗性血小板抑制与轻度创伤性ICH的放射性或临床恶化增加无关.
  • 这些发现挑战了对这种患者群体抗血小板药物风险的假设.
  • 重新评估目前的指导方针和风险分层策略是有必要的,可能利用前性研究.