迪波特里奥塞法卢斯 (dibothriocephalus nihonkaiensis) 感染伴有维生素B缺乏:一个病例报告
Kyoko Yoshida1, Masahiko Saito2, Akiko Sumiyoshi2
1Department of Infectious Diseases, Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagomge, Bunkyo, Tokyo, 113-8677, Japan.
概括
这项研究报告了第一个与维生素B12缺乏相关的Dibothriocephalus nihonkaiensis感染病例. 治疗解决了缺陷,突出了对这种带状虫感染的临床见解.
科学领域:
- 传染性疾病 传染性疾病
- 寄生虫学的寄生虫学
- 胃肠病学 胃肠病学
背景情况:
- 双胞胎虫病是一种带状虫感染,源于食用生鱼或未煮熟的鱼.
- 狄波特里奥塞法卢斯 (Dibothriocephalus nihonkaiensis) 是人类第二大流行线虫物种,每年造成2000多例感染.
- 虽然已知Dibothriocephalus latus会导致维生素B12缺乏,但这种并发症之前没有报告过D. nihonkaiensis.
研究的目的:
- 报告与维生素B12缺乏相关的第一个分子确诊的Dibothriocephalus nihonkaiensis感染病例.
- 描述D. nihonkaiensis感染和维生素B12缺乏症患者的临床表现和实验室发现.
- 为了解D. nihonkaiensis感染的潜在并发症做出贡献.
主要方法:
- 一个19岁的男性被怀疑感染D. nihonkaiensis的病例报告.
- 分子确认了Dibothriocephalus nihonkaiensis的存在.
- 抗甲虫治疗前后对维生素B12水平和临床症状的监测.
主要成果:
- 患者在食用生鱼后出现了带状虫的分泌物.
- 最初的实验室数据显示,维生素B12水平略有下降,在两个月内进一步下降.
- 抗甲虫治疗后,维生素B12水平自发正常化,没有出现贫血的发展.
结论:
- 这一病例是第一个与维生素B12缺乏相关的Dibothriocephalus nihonkaiensis感染的分子证明实例.
- 这些发现表明,D. nihonkaiensis感染可能导致维生素B12缺乏.
- 在治疗后自发解决维生素B12缺乏症,为D. nihonkaiensis感染提供了宝贵的临床见解.
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