轨道肌肉炎:一种不常见的眼科表现在多样性硬化症-多样性肌肉炎重叠综合征中
Shan Kai Ing1,2, Guo Ruey Ling3,4, Yih Hoong Lee2
1Faculty of Medicine, SEGi University, Sibu Clinical Campus, Sibu, Sarawak, Malaysia shankai1992@gmail.com.
BMJ case reports
|September 24, 2025
概括
硬化症-多聚肌炎重叠综合征 (SSc-PM) 很少会出现轨道肌炎. 在这种情况下,早期识别和免疫抑制治疗导致眼部症状完全消失.
科学领域:
- 类风湿病学 类风湿病学
- 眼科医生 眼科 眼科
- 神经学 神经学
背景情况:
- 结核多样性肌肉炎重叠综合征 (SSc-PM) 是一种罕见的自身免疫性疾病,结合了系统性硬化和炎症性肌肉病的特征.
- 在SSc-PM中的眼部表现不常见,在医学文献中记录不充分.
研究的目的:
- 报告一种罕见的SSc-PM病例,主要表现为轨道肌肉炎.
- 强调识别和治疗SSc-PM中的眼部参与的重要性.
主要方法:
- 一个中年妇女患有SSc-PM的病例报告.
- 临床表现包括双眼视和限制眼动.
- 诊断工作包括眼科评估,成像和实验室测试 (肌酸激酶,ANA,抗Ku抗体).
主要成果:
- 患者呈现双侧侧直肠肌炎作为主要表现.
- 用甲基prednisolone,prednisolone和mycophenolate mofetil的治疗导致双眼视完全消失.
- 肌肉酶水平正常化,在随访期间没有观察到皮肤或肺部疾病的进展.
结论:
- 轨道肌炎可能是SSc-PM的罕见但可治疗的初始表现.
- 及时诊断和免疫抑制疗法对于管理SSc-PM的眼部并发症至关重要.
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