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Updated: Jan 17, 2026

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使用RNA测序数据预测无意义介导的mRNA衰变从接事件在败血症使用RNA测序数据

Jaewook Shin1, Alger M Fredericks1, Brandon E Armstead1

  • 1Division of Surgical Research, Department of Surgery, Rhode Island Hospital/Alpert Medical School of Brown University, Providence, RI, USA.

Life science alliance
|September 24, 2025
PubMed
概括

替代拼接 (AS) 和无意中介的mRNA衰变 (NMD) 是关键的基因表达调节者. 一项新的NMD管道揭示了败血症患者的NMD比率更高,表明异常拼接与严重疾病和死亡率有关.

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