战争对乌克兰抗菌素耐药性和伤口感染细菌学概况的影响
Viktoriia M Holubnycha1, Olena V Kholodylo2
1Sumy State University, Sumy, Ukraine. v.golubnichaya@med.sumdu.edu.ua.
Communications medicine
|September 24, 2025
概括
乌克兰士兵的与战争有关的伤口显示出多种耐药细菌的高患病率,主要是グラム阴性细菌. 这使愈合复杂化,并增加了在医院传播抗菌素耐药性的风险.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 战争带来了重大的公共卫生挑战,特别是感染和抗菌素耐药性.
- 这项研究调查了战争对乌克兰民用医院的伤口微生物群和抗菌素耐药性的影响.
研究的目的:
- 评估战争对乌克兰民用医院治疗的患者伤口微生物组的影响.
- 确定从战斗伤口中分离出来的细菌中抗菌素耐药性的分布.
主要方法:
- 来自乌克兰东北部接受治疗的73名士兵的伤口样本分析 (2024年1月至4月).
- 识别孤立的微生物并评估它们的抗微生物耐药性概况.
主要成果:
- 在56.16%的样本中发现了细菌,其中格拉姆阴性细菌占主导地位.
- 关键的分离物包括Acinetobacter baumannii (36%),Enterococcus faecalis (12%) 和Bacillus cereus (12%) 等.
- 观察到高频率的多药性耐药性 (84.6%),其中グラム阴性细菌的耐药性更高.
结论:
- 格拉姆阴性细菌主导军事人员的伤口感染,经常表现出多种药物耐药性.
- 这些耐药菌株阻碍了伤口愈合,并促进了医疗机构内的抗菌素耐药性的传播.
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