通过深度学习模型在心声图中自动检测新生儿肺高血压
Holger Michel1, Ece Ozkan2, Kieran Chin-Cheong2
1University of Regensburg Faculty of Medicine, University Children's Hospital Regensburg (KUNO), Hospital St. Hedwig of the Order of St. John, Regensburg, Germany. Holger.Michel@klinik.uni-regensburg.de.
Pediatric research
|September 24, 2025
概括
一个新的深度学习模型使用心声学在婴儿中准确检测肺高血压 (PH). 这种自动化方法为早期PH诊断提供了一种可复制和可解释的工具,有可能改善婴儿的结果.
科学领域:
- 心脏病学 心脏病学
- 人工智能的人工智能
- 医疗成像医学成像
背景情况:
- 婴儿肺高血压 (PH) 会增加发病率和死亡率.
- 对于PH诊断的标准心声回声是耗时的,需要专业知识.
- 建议采用深度学习 (DL) 方法在婴儿心声学中自动检测PH.
研究的目的:
- 开发和验证DL模型用于婴儿的自动PH检测.
- 为了评估模型的准确性,使用缩异心率指数 (EIs) 作为参考.
- 为了评估模型在不同回声心脏学视图和架构的性能.
主要方法:
- 利用975个培训/验证和378个婴儿 (3-90天) 的心声回声录像视频.
- 使用空间和空间时间卷积神经网络 (CNN) 进行PH预测模型培训.
- 应用梯度加权类激活映射用于模型可解释性.
主要成果:
- 横侧短轴视图实现了最高的单视图性能 (AUROC高达0.94).
- 结合三个视图,提高了准确性 (AUROC高达0.96).
- Saliency 地图突出显示了临床上相关的区域,如腹腔间隔膜.
结论:
- DL模型证明了新生儿自动化PH检测的高准确性,可解释性和可重复性.
- 该模型显示了作为例行PH查的可扩展工具的潜力.
- 这项研究证实了时空CNN在非侵入性婴儿诊断中的实用性.
相关概念视频
Assessing Blood pressure using a doppler ultrasound
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Assessing Blood Pressure
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.
Measurement of Blood Pressure
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.
Neural Regulation of Blood Pressure
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...


