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相关概念视频

Cis-regulatory Sequences02:02

Cis-regulatory Sequences

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Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
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Cis-regulatory Sequences02:02

Cis-regulatory Sequences

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Overview of Transposition and Recombination02:13

Overview of Transposition and Recombination

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Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
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Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

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Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome.  Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form...
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Cell Signaling in Plants01:25

Cell Signaling in Plants

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Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
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Combinatorial Gene Control02:33

Combinatorial Gene Control

9.5K
Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
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相关实验视频

Updated: Jan 17, 2026

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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监管要素:系统的识别和园艺应用.

Tian Li1, Wen Zeng1,2, Fangjie Zhu1

  • 1Haixia Institute of Science and Technology, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, College of Horticulture, National Engineering Research Center of JUNCAO, Fujian Agriculture and Forestry University, Fuzhou, 350002 China.

aBIOTECH
|September 25, 2025
PubMed
概括

识别 cis 调节元件 (CREs) 是理解基因调节和改善作物的关键. 本综述涵盖了CRE识别方法及其在园艺作物育种中用于增强特征的应用.

关键词:
繁殖 繁殖 繁殖 繁殖关联调节元素的关联调节元素.具有DNA结合特异性.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.基因监管网络 基因监管网络园艺作物 园艺作物

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Quantitative Comparison of cis-Regulatory Element CRE Activities in Transgenic Drosophila melanogaster
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Quantitative Comparison of cis-Regulatory Element CRE Activities in Transgenic Drosophila melanogaster

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Using SCOPE to Identify Potential Regulatory Motifs in Coregulated Genes
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Using SCOPE to Identify Potential Regulatory Motifs in Coregulated Genes

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相关实验视频

Last Updated: Jan 17, 2026

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Quantitative Comparison of cis-Regulatory Element CRE Activities in Transgenic Drosophila melanogaster
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Quantitative Comparison of cis-Regulatory Element CRE Activities in Transgenic Drosophila melanogaster

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科学领域:

  • 基因组学就是基因组学.
  • 分子生物学分子生物学
  • 植物科学 植物科学

背景情况:

  • 基因调节元件 (CREs) 是DNA片段,它们与转录因子 (TFs) 结合,以控制基因表达.
  • CREs充当分子开关,调节基因表达剂量,时间和位置.
  • 了解CREs对于注释基因组和破译基因调节网络至关重要.

研究的目的:

  • 审查用于识别CREs的高通量方法.
  • 为了说明CRE与园艺作物的农学特征之间的联系.
  • 讨论利用CREs进行作物育种.

主要方法:

  • 审查目前用于CRE识别的高通量技术.
  • 对CRE和农学特征的现有文献进行分析.
  • 讨论涉及CREs的基因工程策略.

主要成果:

  • 系统的CRE识别有助于功能性基因组注释.
  • CREs与园艺作物的各种农学特征有关.
  • CREs为基因工程提供了精确的目标.

结论:

  • 高通量方法可以实现全面的CRE识别.
  • 利用CREs可以加速改良园艺作物的繁殖.
  • 精准农业和作物改进中,CREs是有价值的目标.