在诊断多发性硬化和视神经炎的视觉功能
Bardia Behnia1, Ameer Mohammed Hadi Layedh2, Hassan Hashemi3
1Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran 1983963113, Iran.
International journal of ophthalmology
|September 25, 2025
概括
多发性硬化症 (MS) 影响折射误差和对比度敏感性 (CS). 视神经炎 (ON) 在MS患者中进一步减少CS,突出显示视觉功能.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 视觉科学 视觉科学
背景情况:
- 多发性硬化症 (MS) 是一种影响中枢神经系统的脱髓化疾病.
- 视神经炎 (ON) 是MS的常见早期症状,影响视觉通路.
- 视觉功能缺陷在MS患者中很普遍,影响生活质量.
研究的目的:
- 评估各种视觉功能的诊断能力,以区分多发性硬化症患者与健康对照.
- 评估MS患者的视觉功能变化,有或没有ON病史.
- 确定特定的可视参数,可以帮助MS诊断和监测.
主要方法:
- 一项横截面研究,比较MS患者的折射误差,视敏度 (VA) 和对比敏感度 (CS),并匹配健康对照.
- 多发性硬化患者被分为具有和没有ON的群体.
- 进行了统计分析,以确定不同视觉参数的灵敏度和特异性.
主要成果:
- 与对照组相比,多发性硬化患者的最佳校正视敏度 (BCVA) 降低,球形折射误差发生变化.
- 在多发性硬化患者中,对比度敏感性 (CS) 在每度6和18个周期 (CPD) 下降.
- 在MS患者的3个CPD中进一步降低了CS. 6个CPD的圆柱形组件和CS显示出高灵敏度来区分MS组,而12个CPD的BCVA和CS显示出高特异性.
结论:
- 折射误差和CS受到MS的显著影响,ON加剧了CS赤字.
- 视觉功能评估,包括折射误差和CS,是MS监测和管理的宝贵工具.
- 这些发现强调了全面视觉检查在治疗多发性硬化症患者中的重要性.
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