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Updated: May 3, 2026

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通过激活Itga6-PI3K/AKT信号通路,在上用含的酸涂层进行快速的骨质整合

Xi Wang1, Tiantian Chen2, Peng Pan2

  • 1Department of Emergency and Oral Medicine, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, China.

Materials today. Bio
|September 25, 2025
PubMed
概括

研究人员开发了一种含的酸涂层,用于骨修复材料. 这种表面修饰通过PI3K/AKT通路促进细胞分化,从而增强骨整合.

关键词:
氧亚帕提特是一种氧亚帕提特.骨质整合 骨质整合是的组成部分.坦坦是一种.

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The mammalian target of rapamycin  (mTOR) is a serine/threonine kinase that regulates growth, proliferation, and cell survival in response to hormones, growth factors, or nutrient availability. This kinase exists in two structurally and functionally distinct forms: mTOR complex 1  (mTORC1) and mTOR complex 2  (mTORC2). The first form (mTORC1) is composed of a rapamycin-sensitive Raptor and proline-rich Akt substrate, PRAS40. In contrast,  mTORC2 consists of a...
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