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Updated: Jan 17, 2026

Modeling Chemotherapy Resistant Leukemia In Vitro
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避难所:骨髓纤维细胞内活着的CLL细胞及其对残留疾病持续性的影响

Pin Lu1,2, Carrie A Franzen3, Aldana Vistarop1

  • 1Cancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, PA.

Blood neoplasia
|September 25, 2025
PubMed
概括

细胞内细胞结构允许慢性淋巴细胞白血病 (CLL) 细胞逃避布鲁顿氨酸激酶抑制剂 (BTKis),作为最小残留疾病 (MRD) 持续存在. 向CXCR4可能会克服这种治疗抵抗.

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