178个国家和地区与城市化相关的结核病负担的差异:一项观察性研究
Yaping Wang1,2, Qiao Liu1,2, Zhongdan Chen3
1Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Frontiers in public health
|September 25, 2025
概括
在全球范围内,城市化显著减少了多耐药结核病 (MDR-TB) 和广泛耐药结核病 (XDR-TB). 然而,城市化增加了中高收入国家的MDR-TB和XDR-TB负担,凸显了健康城市发展的必要性.
科学领域:
- 全球健康 全球健康
- 城市研究 城市研究
- 传染病流行病学 传染病流行病学
背景情况:
- 结核病 (TB) 是全球主要的传染性死亡原因.
- 将城市化与结核病负担联系起来的数量证据有限.
- 本研究评估了城市化与全球结核病负担之间的关系.
研究的目的:
- 评估城市化对全球结核病负担的影响.
- 分析城市化与总结核病,耐药性结核病 (DS-TB),多耐药性结核病 (MDR-TB) 和广泛耐药性结核病 (XDR-TB) 的发病率,流行率和死亡率之间的关联.
主要方法:
- 开发了178个国家 (2012-2019) 的综合城市化指数,使用人口,卫生,夜间照明,NDVI和GDP数据.
- 采用固定效应线性模型来估计城市化与结核病指标之间的关联.
- 分析了总结核病及其亚型 (DS-TB,MDR-TB,XDR-TB),考虑到一年的滞后.
主要成果:
- 较高的城市化得分与全球MDR-TB和XDR-TB发病率,流行率和死亡率的显著减少有关.
- 城市化和总结核病或DS-TB之间没有发现显著的关联.
- 城市化与中高收入国家中MDR-TB和XDR-TB负担的增加有关.
结论:
- 城市化与减少MDR-TB和XDR-TB的全球负担有关.
- 城市化与中高收入国家中MDR-TB和XDR-TB负担的增加有关.
- 发展健康,管理良好的城市对于预防和控制结核病至关重要,特别是在转型经济体.
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