多种针治疗在初级失眠中的有效性和安全性:贝叶斯网络元分析
Liguo Liu1,2, Yiming Chen3, Minne Tian4
1The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, PR China.
Integrative medicine research
|September 25, 2025
概括
针疗法在治疗原发性失眠方面表现出比催眠药更高的疗效,如AT与催眠疗法 (MOX) 和AT与耳鼻治疗 (AU) 等特定组合最有效. 针点猫肠嵌入 (ACE) 也显示出高临床有效性与可靠的安全性.
科学领域:
- 综合医学是一个整体的医学.
- 睡眠科学 睡眠科学
- 基于证据的实践.
背景情况:
- 主要失眠是一种普遍的睡眠障碍.
- 针 (AT) 治疗因其在治疗初级失眠方面的有效性而得到认可.
- 缺乏对各种AT疗法和传统催眠药进行全面的比较.
研究的目的:
- 进行一个网络元分析,比较多种针疗法的疗效和安全性与治疗原发性失眠的催眠药.
- 确定最有效的AT干预措施,以改善睡眠质量和临床结果.
主要方法:
- 在8个数据库中进行了系统的搜索,直到2024年7月为随机对照试验 (RCT) 进行了系统的搜索.
- 包括集中于治疗原发性失眠的针治疗的RCT.
- 匹兹堡睡眠质量指数 (PSQI) 评分和临床有效率用网络元分析提取和分析.
主要成果:
- 分析了64个涉及4443名患者的RCT.
- 与催眠药相比,多种AT疗法在改善PSQI得分方面表现出更高的疗效.
- 针结合 (MOX) 和针结合耳鼻治疗 (AU) 被确定为改善PSQI得分的最有效干预措施.
- 点猫肠嵌入 (ACE) 显示出临床有效性的最大潜力.
- 对于任何一种AT疗法,没有报告任何严重不良事件.
结论:
- 与催眠药相比,大多数AT疗法有效地改善了初级失眠的睡眠指标和临床结果.
- 与AU结合的AT,与MOX结合的AT和ACE是特别有前途的干预措施.
- 抗逆转录疗法具有可靠的安全性.
- 纳入试验的整体质量很低,需要更高质量的RCT来获得强有力的证据.
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