纯与混合斯特鲁维特石形成者的代谢异常:使用大型语言模型进行数据提取的回顾性比较分析
Juanita Velasquez Ospina1, Ansh Bhatia2, Archan Khandekar1
1Desai Sethi Urology Institute University of Miami, Miller School of Medicine Miami Florida USA.
BJUI compass
|September 25, 2025
概括
在形成纯 struvite 石头和混合 struvite-calcium oxalate 石头的患者中,代谢异常很常见. 建议对感染相关的结石进行常规代谢评估,以指导管理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 生物化学 生物化学
背景情况:
- 斯特鲁维特石是感染相关的石头,通常与代谢异常有关.
- 了解纯与混合的 struvite 石的代谢概况对于有效的管理至关重要.
研究的目的:
- 为了比较纯 struvite 石头与混合 struvite 和酸盐石头患者的人口特征和代谢异常.
主要方法:
- 对3001个石头分析的回顾性审查 (2019年8月 - 2024年4月).
- 包括患有24小时尿路结石风险概况的患者;不包括患有先前结石或特定疾病的患者.
- 使用LLM增强管道提取的人口统计数据,并发病情况和实验室值;与纯 struvite 和混合石相比较.
主要成果:
- 其中41名患者包括:21名纯斯特鲁维特石,20名混合石.
- 纯斯特鲁维特石在女性中更频繁,但在统计学上并不显著.
- 在纯 struvite 组中较低的尿氧酸,,酸盐和尿酸 (不显著).
- 在纯 struvite 组中,brushite,酸盐和酸盐的超和度显著降低 (P < 0.05).
- 代谢异常的高患病率:在纯石中90.5%,在混合石中100%.
结论:
- 代谢异常在纯粹的和混合的 struvite 石头形成者中非常普遍.
- 这些发现支持对感染相关的结石进行常规代谢评估.
- 这种评估有助于指导石头复发的长期管理策略.
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