孕期高血压疾病的可修改风险因素
Mei-Wei Chang1, Alai Tan1, Joshua M Smyth2
1The Ohio State University College of Nursing.
Critical public health
|September 25, 2025
概括
微量营养素的摄入,包括叶酸和维生素B12,以及心理困扰与妊娠高血压障碍 (HDPs) 有关. 这些关联在整个怀孕过程中发生变化,突出了潜在的干预领域.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇健康 孕产妇健康
- 营养科学 营养科学
背景情况:
- 孕期高血压疾病 (HDPs) 是全球孕产妇死亡率和发病率的主要原因.
- 了解微量营养素状况和心理健康等促成因素对于改善孕产妇的结果至关重要.
研究的目的:
- 调查微量营养素摄入量 (叶酸盐,维生素B12) 和心理困扰 (感知压力,产前困扰,产前抑郁) 与HDPs之间的关联.
- 检查这些关联在不同的妊娠年龄之间如何变化.
主要方法:
- 纵向研究收集三个时间点的数据:≤17周 (T1),25-27周 (T2) 和35-37周怀孕 (T3).
- 评估了微量营养素摄入量 (叶酸盐,维生素B12) 和心理困扰措施.
- 使用T测试来比较具有和没有HDPs的参与者.
主要成果:
- 较低的叶酸和维生素B12摄入量与T1和T2的HDPs有关.
- 心理困扰与HDPs呈现积极关联,在各种措施和时间点之间具有不同的强度:产前困扰 (所有T),感知压力 (T3) 和产前抑郁 (T2,T3).
结论:
- 微量营养素状况和心理痛苦都与HDPs的发展有显著的关联.
- 这些关联的强度和性质取决于特定的微量营养素或心理测量和妊娠阶段.
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