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流浪和拥有的动物中的SOD1和CAT基因表达

Gonca Sonmez¹, Mehmet Cevat Temizkan², Muhammed Hudai Culha¹

¹Department of Genetics, Faculty of Veterinary Medicine, Selcuk University, Konya, Turkiye.

Veterinarni medicina

|September 25, 2025

概括

像狗和猫这样的伴侣动物经历压力,影响他们的健康. 这项研究发现了所有和流浪动物之间的抗氧化基因表达的差异,这表明生活方式会影响氧化压力.

科学领域:

兽医医学兽医医学兽医医学
动物生理学动物生理学
环境健康环境健康

背景情况:

城市环境中的伴侣动物 (狗和猫) 面临着不同的生活条件.
流浪动物暴露于慢性压力,可能导致氧化应激和细胞损伤.
氧化应激是由于 redox 恒温的不平衡造成的,其特点是反应性氧物种的积累.

研究的目的:

为了研究抗氧化剂防御基因 (SOD1和CAT) 的表达水平,在拥有的与流浪狗和猫之间.
为了确定环境条件和生活方式是否影响伴侣动物的氧化应激标志物.

主要方法:

从150只雌性动物 (90只狗,60只猫) 收集了血液样本.
周围血液单核细胞 (PBMC) 被分离出来用于RNA提取.
使用定量实时聚合酶链反应 (qPCR) 来测量SOD1和CAT基因表达.

主要成果:

拥有动物的SOD1表达水平与流浪动物相比显著更高 (P < 0.01).
与流浪动物相比,CAT表达水平显示,拥有的动物相对于流浪动物的数量没有显著下降.
抗氧化剂防御的基因表达在拥有的和流浪的伴侣动物之间有所不同.

结论:

伴侣动物之间的抗氧化基因表达因其生活条件和生活方式而异.
环境因素和生活方式在调节狗和猫的氧化压力方面起着至关重要的作用.
这突显了压力和环境对伴侣动物生理健康的影响.

关键词:

狗狼 (Canis lupus familiaris) 是一个流感的动物.猫 (Felis catus) 是一种动物.抗氧化剂是一种抗氧化剂.基因表达的基因表达方式

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