怀孕期间阻塞性睡眠呼吸暂停的查问卷的诊断准确性:一个元分析和更新的系统审查
Marco La Verde1, Esposito Renata2, Maria Maddalena Marrapodi3,4
1Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Journal of sleep research
|September 25, 2025
概括
像柏林问卷和ESS这样的标准阻塞性睡眠呼吸暂停 (OSA) 查工具显示,孕妇的诊断准确性很差. 需要新的,针对怀孕的查方法,以便在妊娠期间更好地检测OSA.
科学领域:
- 产科和妇科 产科和妇科
- 睡眠医学 睡眠医学
- 诊断准确性研究 诊断准确性研究
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 越来越多地被认为是怀孕期间的一个重大问题.
- 目前存在的OSA查工具尚未在孕妇群体中得到充分验证.
- 准确的查对于及时干预和管理孕妇OSA至关重要.
研究的目的:
- 为了评估常见阻塞性睡眠呼吸暂停 (OSA) 查工具在孕妇的诊断性能.
- 评估广泛使用的睡眠问卷对OSA查在这个人口群体中的有效性.
- 确定需要特定于怀孕的OSA查仪器的需求.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在MEDLINE,Scopus,Cochrane CENTRAL和谷歌学者 (直到2024年3月) 的综合文献搜索.
- 包括研究比较OSA查问卷与孕妇的夜间多睡眠学 (PSG);敏感性,特异性,DOR和LR的计算.
主要成果:
- 分析了8项涉及10,043名孕妇的研究,OSA患病率从12%到72.3%不等.
- 柏林调查问卷在敏感性和特异性方面表现出显著的异质性,敏感性和假阳性率之间存在强烈的正相关性.
- 爱普沃思睡眠度量表 (ESS) 也显示了相当大的变化和敏感性和错误阳性之间的正相关性.
结论:
- 传统的OSA查工具,包括柏林问卷和ESS,在孕妇人群中显示出诊断准确度较差.
- 显然需要开发和验证专门针对OSA在怀孕期间量身定制的新型查仪器.
- 需要进一步的研究,以了解孕妇独特的OSA风险因素.
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