brojler对饮食中的不同酵母细胞壁成分的反应受到Salmonella typhimurium的挑战
Pinar Sacakli1, Elsayed Mickdam2, Alev Gurol Bayraktaroglu3
1Department of Animal Nutrition & Nutritional Diseases, Faculty of Veterinary Medicine, Ankara University, Ankara, 06110, Turkey.
Veterinary research communications
|September 25, 2025
概括
饮食酵母细胞壁补充剂改善了肉的生长和肠道健康,即使受到沙门氏菌Typhimurium的挑战. 这种益生菌策略增强了体重,体重增加和肠道屏障功能.
科学领域:
- 动物科学动物科学
- 禽类的营养 养
- 微生物学 微生物学
背景情况:
- 沙门氏菌Typhimurium感染对肉的健康和表现构成重大挑战.
- 正在探索饮食干预措施,如益生菌补充剂,以减轻这些挑战.
- 酵母衍生产品以其调节肠道微生物群和免疫反应的潜力而闻名.
研究的目的:
- 评估不同饮食益生菌补充剂的疗效,包括酵母细胞壁,在受到沙门氏菌Typhimurium挑战的肉上.
- 评估这些益生菌对生长性能,肠道组织学和与肠道屏障相关的基因表达的影响.
主要方法:
- 两项实验涉及肉食用各种益生菌补充的饮食 (自解全酵母细胞,酵母细胞壁,mannan-oligosaccharides + β-glucan).
- 实验II包括一个沙门氏菌Typhimurium挑战.
- 分析了生长参数,阴和骨组织学 (骨高度,密室深度) 和基因表达 (克劳丁,IL-1β,IL-10,奥克卢丁).
主要成果:
- 用酵母细胞壁 (CELL组) 补充剂在两个实验中显著改善了最终的体重和体重增加.
- 肠道组织学显示出多种影响,其中一些益生菌影响了的高度和密室深度.
- 基因表达分析显示,与肠道屏障和免疫反应相关的基因发生了显著的变化.
结论:
- 饮食中的益生菌补充剂,特别是酵母细胞壁,对肉的表现和肠道健康产生积极影响.
- 酵母细胞壁补充剂增强了肠道屏障功能,并调节了受挑战的鸟类的免疫基因表达.
- 益生菌是一种有前途的策略,可以提高肉对肠道病原体的抵抗力.
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