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Updated: Jan 17, 2026

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在神经元胺合成酶缺陷的起源的个体脂质变化

Anna B Ziegler1,2, Cedrik Wesselmann2, Konstantin Beckschäfer3

  • 1Dendrite Differentiation, German Center for Neurodegenerative Diseases, Bonn, Germany.

PLoS genetics
|September 25, 2025
PubMed
概括

8型渐进性肌性 (PME8) 涉及胺合成酶 (CerS) 损失,导致和神经退行. 恢复Drosophila神经元中的特定胺可以挽救缺陷,从而揭示了PME8的治疗点.

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