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胰岛素样生长因子I和Progranulin对人类热细胞模型的影响

Makoto Osaka1, Atsushi Tajima1, Satoshi Takemori1

  • 1Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Tokyo 181-8611, Japan.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
|September 25, 2025
PubMed
概括

益格拉努林 (PGRN) 可以抑制胰岛素样生长因子-1 (IGF-I) 诱导的热囊细胞增殖,特别是在低度的IGF-I时. 这种相互作用可能涉及调节Erk1/2酸化,影响胎盘生长.

关键词:
细胞的增殖细胞的增殖.孕期糖尿病 孕期糖尿病人类热细胞细胞.胰岛素类生长因子-I在JEG-3细胞中,益格拉努林是一种Progranulin.

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