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Updated: Jul 15, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
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[微轴流量:临床证据和指导方针]

Koichi Toda1

  • 1Department of Cardiovascular Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan.

Kyobu geka. The Japanese journal of thoracic surgery
|September 25, 2025
PubMed
概括

微轴流量的Impella装置有效地卸载左心室,以帮助心脏性休克患者恢复. 在日本的广泛使用表明了出色的临床结果,支持其作为最少侵入性治疗的作用.

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ATP Driven Pumps II: P-type Pumps01:34

ATP Driven Pumps II: P-type Pumps

The P-type pumps are a large family of integral membrane transporter ATPases. They are divided into five major types based on substrate specificity, from I to V.
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...