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Updated: Jan 16, 2026

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis
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Published on: December 14, 2015

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与疾病相关的调节性DNA变体和表皮的恒常转录因子

Douglas F Porter1, Robin M Meyers2,3, Weili Miao2

  • 1Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, USA. dfporter@stanford.edu.

Nature communications
|September 25, 2025
PubMed
概括

研究人员通过分析转录因子结合来确定影响皮肤平衡的遗传变异. 这揭示了被破坏的表皮分化是多原性皮肤疾病的关键机制,涉及到特定的TF家族的疾病风险.

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