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候选素的动态表达促进了Candida albicans在小鼠的口腔殖民

Ricardo Fróis-Martins1,2, Julia Lagler1,2, Tim B Schille3,4

  • 1Section of Immunology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.

Nature microbiology
|September 25, 2025
PubMed
概括

虫 Candida albicans 使用形和毒素 candidalysin 来殖民口腔. 这一过程对于真菌建立其利基和逃避口腔粘膜中的免疫防御至关重要.

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Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...