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EpiAgent:为单细胞表观基因组学的基础模型.

Xiaoyang Chen1, Keyi Li1, Xuejian Cui1

  • 1Ministry of Education Key Laboratory of Bioinformatics, Bioinformatics Division at the Beijing National Research Center for Information Science and Technology, Center for Synthetic and Systems Biology, Department of Automation, Tsinghua University, Beijing, China.

Nature methods
|September 25, 2025
PubMed
概括

EpiAgent是一种用于分析单细胞ATAC测序 (scATAC-seq) 数据的新基础模型. 它有效地编码细胞染色质模式,有助于细胞类型的注释和预测细胞对干扰的反应.

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Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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