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Updated: Jan 16, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
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在中国东部对人类乳头瘤病毒31型和33型变种的遗传学和选择性压力分析

Yan Wang1,2,3, Wenjie Qu1, Qi Zhou1

  • 1Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Obstetrics & Gynecology Hospital of Fudan University, Shanghai, 200433, China.

BMC infectious diseases
|September 26, 2025
PubMed
概括

这项研究确定了与子宫病变有关的特定的人类乳头瘤病毒31型 (HPV31) 和HPV33遗传变异. 结果揭示了两个关键突变和11个被积极选择的部位,为中国东部的疫苗开发提供了洞察力.

关键词:
中国东部的中国东部.人类乳头瘤病毒31和33人类遗传学分析选择性的压力选择性压力.

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相关概念视频

Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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