预后营养指数,肉症和死亡风险:一项基于全国人口的研究
Qian Wu1, Wenquan Ding1, Dongqing You2
1Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Jiangsu, China.
Nutrition & metabolism
|September 26, 2025
概括
预后营养指数 (PNI) 是识别麻症和预测美国成年人死亡率的关键指标. 较高的PNI水平与降低了肉症和死亡风险有关,突出了其预后价值.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 心血管健康 心血管健康
背景情况:
- 营养状况显著影响了sarcopenia患者的预后,但其预测作用需要进一步阐明.
- 预后营养指数 (PNI) 结合了血清白蛋白和淋巴细胞计数,提供了营养状况的潜在标志物.
研究的目的:
- 调查预后营养指数 (PNI) 与美国成年人肉类的患病率之间的联系.
- 评估PNI对萨尔科佩尼亚患者的整体和心血管死亡率的影响.
主要方法:
- 对18岁以上成年人NHANES数据 (1999-2004,2011-2018) 的回顾性分析.
- 使用血清白蛋白和淋巴细胞计数计算PNI;根据既定标准评估肉类.
- 使用多变量逻辑回归,考克斯回归和卡普兰-梅尔生存分析.
主要成果:
- 在24,661名参与者中,11.19%的参与者被发现患有肉症.
- 较高的PNI四分位数与显著较低的肉类的几率 (OR 0.43) 和所有原因 (HR 0.64) 和心血管死亡率 (HR 0.60) 的风险降低相关.
- 在子组分析和先进的统计建模中,研究结果保持一致.
结论:
- 预后营养指数 (PNI) 独立预测了美国成年人的肉症,全因死亡率和心血管死亡率.
- PNI作为一种有价值的工具,用于对患有肉类的个体进行风险分层.
- 早期识别高风险个体可以告知有针对性的干预措施,以改善健康结果.
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