来自Streptococcus suis血清型2的RfeA触发NLRP3/Caspase-1-依赖性热,导致血脑屏障的破坏

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Shuai Gao1, Wentao Wu2, Xingxing Xiao3

  • 1Wenzhou Key Laboratory of Sanitary Microbiology, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325035, China. 1359790915@qq.com.

Veterinary research
|September 26, 2025
PubMed
概括

杆菌 suis 血清型 2 (SS2) 外蛋白 A (RfeA) 在脑细胞中触发热,突破血脑屏障 (BBB). 这一发现为SS2脑膜炎提供了潜在的治疗点.

关键词:
链球菌 suis 血清型 2 类型在NLRP3/Caspase-1中使用.在RfeAA.血脑屏障 血脑屏障 血脑屏障 血脑屏障热致灭 (pyroptosis) 是一种致的过程.

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