Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

982
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
982
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

788
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
788

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Traction Force Microscopy for Viscoelastic Substrates: A Semi-Analytical Method.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Mechanical and Electrical Phenotype of hiPSC-Cardiomyocytes on Fibronectin-Based Hydrogels.

Advanced healthcare materials·2025
Same author

3D Bioprinted Engineered Living Microreactors for Continuous Organophosphorus Compound Degradation.

Small science·2025
Same author

Piezo1 regulates the mechanotransduction of soft matrix viscoelasticity.

Nature communications·2025
Same author

Tunable network architecture in a hydrogel with extreme vibration damping properties.

Communications materials·2025
Same author

NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin-Binding Integrins.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025

相关实验视频

Updated: Jan 16, 2026

Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice
12:12

Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice

Published on: February 8, 2016

13.0K

以益生菌为基础的材料作为活体疗法

Laura Sabio1, Graham J Day1, Manuel Salmeron-Sanchez1,2,3

  • 1Centre for the Cellular Microenvironment (CeMi), University of Glasgow, University Avenue, Glasgow, G12 8QQ, United Kingdom.

Advanced materials (Deerfield Beach, Fla.)
|September 26, 2025
PubMed
概括

工程生物材料 (ELM),特别是益生菌生物材料 (PLM),提供有针对性的疗法,但需要改进的遗传工具和临床使用的安全规定. 应对这些挑战将释放PLM在各种生物医学应用中的全部潜力.

关键词:
工程生物材料是生物材料.益生菌是一种益生菌.治疗药物 治疗药物

更多相关视频

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
06:07

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells

Published on: June 13, 2020

7.1K
Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

25.1K

相关实验视频

Last Updated: Jan 16, 2026

Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice
12:12

Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice

Published on: February 8, 2016

13.0K
Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells
06:07

Evaluating Cell Death Using Cell-Free Supernatant of Probiotics in Three-Dimensional Spheroid Cultures of Colorectal Cancer Cells

Published on: June 13, 2020

7.1K
Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

25.1K

科学领域:

  • 生物材料科学 生物材料科学
  • 合成生物学 合成生物学
  • 微生物学 微生物学

背景情况:

  • 先进的生物材料对于开发更安全,更有针对性的疗法至关重要.
  • 工程生物材料 (ELM),整合合成生物学和材料科学,显示生物医学应用的希望.
  • 益生菌生物材料 (PLMs) 是一种ELM的子类,在矩阵中使用工程益生菌,与生物治疗产品 (LBPs) 不同.

研究的目的:

  • 审查ELM和益生菌的基本特征.
  • 探索生物医学应用工程PLM的最新进展.
  • 讨论PLM临床实施的生物安全问题和监管缺口.

主要方法:

  • 工程生物材料 (ELM) 和益生菌生物材料 (PLM) 的文献综述.
  • 对PLM设计和应用的最新研究进行分析.
  • 检查生物安全考虑和监管框架.

主要成果:

  • PLM在生物传感,感染治疗,骨修复,伤口愈合,阴道失衡,肠道疾病和癌症治疗方面显示出潜力.
  • 仍然存在重大挑战,包括对益生菌的有限基因工程工具.
  • 像水平基因转移和监管障碍等生物安全问题阻碍了临床翻译.

结论:

  • PLM提供动态和有针对性的治疗策略.
  • 强大的遗传工具包和明确的监管途径对于PLM的安全有效的临床转化至关重要.
  • 需要进一步的研究来克服目前的局限性,特别是对于弱势群体.