在小鼠中通过PTHLH和HHIP活动对冠状和羊毛状穿透性的差异调节

Madrikha D Saturne1, Susan M Motch Perrine2, Qingyang Li1

  • 1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Development (Cambridge, England)
|September 26, 2025
PubMed
概括

由于HH信号的破坏,导致骨突. 在Hhip-/-小鼠中,Pthlh通常会阻止冠状融合,但它缺少导致融合,揭示了它在穿透性中的作用.