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Updated: Jan 16, 2026

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通过PI3Kγ激活驱动的VEGFR2阻断克服了获得的KRAS G12D抑制剂耐药性

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    bioRxiv : the preprint server for biology
    |September 26, 2025
    PubMed
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    克拉斯G12D抑制剂通过VEGFA-VEGFR2信号传递面临抵抗. 将VEGFA-VEGFR2阻塞与KRAS抑制剂结合起来,可以克服胃肠道癌症中的这种抗性.

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