相关实验视频

Updated: Jan 16, 2026

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
09:39

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

Published on: January 27, 2014

13.1K

状螺旋胺增强了D2R与细胞质蛋白的相互作用,以调解持续的D2R激动剂诱导的运动运动抑制

Basant Hens1, Whitney R Smith-Kinneman2,3, Emma H Doud2,3

  • 1Graduate Program in Pharmacology, and Pharmacology.

bioRxiv : the preprint server for biology
|September 26, 2025
PubMed
概括

斯皮诺菲林蛋白对于帕金森病 (PD) 中多巴胺D2受体 (D2R) 功能至关重要. 基因去除斯皮诺菲林降低了D2R激动剂的运动效应,这表明了PD的新治疗点.

关键词:
多巴胺D2受体的受体.互动组互动组是一个互动组.机动车辆 机动车辆 机动车辆蛋白质组学是指蛋白质组学.斯皮诺菲林是人类的一种类型.状体是一个状体.

更多相关视频

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior07:52

In Vivo Wireless Optogenetic Control of Skilled Motor Behavior

Published on: November 22, 2021

3.8K
Rating L-DOPA-Induced Dyskinesias in the Unilaterally 6-OHDA-Lesioned Rat Model of Parkinson's Disease06:45

Rating L-DOPA-Induced Dyskinesias in the Unilaterally 6-OHDA-Lesioned Rat Model of Parkinson's Disease

Published on: October 4, 2021

3.3K

相关概念视频

Desensitization and Tachyphylaxis01:20

Desensitization and Tachyphylaxis

Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
3.0K