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Updated: Jan 16, 2026

Cell Surface Receptor Identification Using Genome-Scale CRISPR/Cas9 Genetic Screens
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表面体CRISPR激活查揭示了调节瘤对NK细胞杀死敏感性的配体

Ravi K Dinesh, Xiaotong Wang, Imran A Mohammad

    bioRxiv : the preprint server for biology
    |September 26, 2025
    PubMed
    概括

    这项研究确定了新的癌症细胞表面蛋白质,包括CD44和Siglec-1,它们调节了自然杀手 (NK) 细胞的杀死. 针对这些分子,如CD43,可以增强NK细胞免疫疗法用于癌症治疗.

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