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在美国更新了查建议后,围产期B组链球菌病的趋势
Anuradha Devabhaktuni1, Neil S Silverman1, Ingmar N Bastian1
1Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California; and the Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.
O&G open
|September 26, 2025
概括
2019年更新的B组链球菌 (GBS) 查指南导致GBS早期发病率和新生儿死亡率显著下降. 查时间的这种变化令人放心,并支持当前的产科实践.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿健康 新生儿健康
- 传染病流行病学 传染病流行病学
背景情况:
- 美国妇产科医生学会在2019年更新了产前B组链球菌 (GBS) 查建议.
- 更新将推的查窗口转移到36 0/737 6/7周的妊娠期.
- 这一变化旨在确保准确的测试结果,为怀孕的个人高达41 0/7周的怀孕.
研究的目的:
- 评估更新的GBS查指南对新生儿GBS早期发病 (EOD) 和死亡率的影响.
- 为了比较疾病和死亡率在指导方针变化之前和之后的时期.
- 评估修订的查时间表的有效性.
主要方法:
- 新生儿GBS EOD和死亡病例的回顾性分析.
- 数据来自疾病控制和预防中心的活性细菌核监测系统.
- 在变更前期 (2016-2018) 和变更后期 (2020-2022) 的利率比较.
主要成果:
- 在转换前的期间报告了总共2,640例病例 (0.24±0.01例/1000活产).
- 在更换后的期间,报告了2,120例病例 (0.20±0.02例/1,000活产).
- 对于GBS EOD的年度百分比变化 (APC) 从变化前期的2.1%下降到变化后期的-9.6%.
结论:
- 新生儿GBS EOD率在更新查指南实施后的三年内显著下降.
- 这些发现支持目前的做法,即改变产前GBS查时间.
- 更新的指导方针似乎有效地减少了新生儿早期出现的GBS疾病的负担.
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