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解锁成功:在试管婴儿患者中,在正常反应的试管婴儿患者中,为叶阶段刺激提供最佳的淋巴腺素起点

Xinyu Nie^1,2, Qi Wang^1,3, Mengmeng Xu⁴

¹Reproductive Medicine Center, Prenatal Diagnosis Center, First Hospital of Jilin University, Changchun, Jilin, People's Republic of China.

International journal of women's health

|September 26, 2025

概括

在晚期黄体阶段 (LPS) 开始淋巴腺素 (Gn) 刺激对体外受精 (IVF) 患者以正常的卵巢反应 (NOR) 是最佳的. 与LPS早期或中期相比,这种时间改善了高质量的胚胎率和临床结果.

科学领域:

生殖内分泌学生殖内分泌学
在体外受精过程中受精.

背景情况:

质阶段刺激 (LPS) 是体外受精 (IVF) 中的卵泡阶段刺激 (FPS) 的替代方案.
确定在正常卵巢响应 (NOR) 患者的LPS中启动淋巴腺素 (Gn) 的最佳时间对于最大限度地提高治疗疗效至关重要.

研究的目的:

为了确定在质阶段刺激 (LPS) 协议中给予淋腺素 (Gn) 的最佳起点.
为了比较不同Gn启动时间在LPS和传统的卵泡阶段刺激 (FPS) 在NOR患者接受试管婴儿/细胞内精子注射 (ICSI) 的疗效.

主要方法:

从2021-2023年对199次试管婴儿/ICSI周期进行了回顾性分析.
患者被分为FPS (n=121) 和LPS (n=78) 组.
为了对结果进行比较分析,LPS组进一步分为早期,中期和晚期GN启动子组.

主要成果:

晚期LPS小组与早期LPS小组相比,显示出高质量的胚胎的比例明显高.
临床怀孕和活产率在LPS后期组略高于LPS早期和中期子组.
晚期LPS组的结果与传统FPS协议所取得的结果相似.

结论:

在晚期的质期启动Gn刺激是NOR患者接受试管婴儿的最佳策略.
这种时间似乎提高了LPS协议中的胚胎质量和临床结果.

关键词:

毛囊阶段卵巢刺激卵巢刺激形期卵巢刺激卵巢刺激正常的卵巢反应正常.怀孕结果怀孕结果淋巴激素启动的时间.

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