非常低出生体重早产婴儿的和摄入量:对骨质疏松症预防和生长的影响
Piyarat Kajohntridach1, Premsak Laoyookhong2, Tippawan Siritientong1,3
1Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathum Wan District, Bangkok, Thailand.
Pediatric gastroenterology, hepatology & nutrition
|September 26, 2025
概括
出生体重非常低 (VLBW) 和骨质疏松症的早产婴儿的和摄入量较低,影响骨生长. 及时补充对于预防骨质疏松症和促进VLBW婴儿的生长至关重要.
科学领域:
- 新生儿医学 新生儿医学
- 儿童营养学 儿童营养学
- 骨的新陈代谢 骨的新陈代谢
背景情况:
- 骨质疏松症是早产婴儿的一个重大问题,特别是那些出生时体重非常低 (VLBW) 的婴儿.
- 足够的和摄入量对于骨矿化和骨生长在这个脆弱群体中至关重要.
- 以前的研究表明,VLBW婴儿的营养摄入量和骨质疏松症的发展之间存在联系.
研究的目的:
- 通过VLBW早产婴儿诊断出骨质疏松症与对照的肠道和肠道途径摄入和的比较.
- 评估营养摄入对VLBW早产婴儿骨质疏松症生长参数的影响.
- 评估营养补充剂与VLBW婴儿骨质疏松症风险之间的关系.
主要方法:
- 进行了一项单一中心的回顾性研究,涉及VLBW早产婴儿 (<1500克).
- 诊断为骨质疏松症的婴儿 (病例组) 与对照婴儿进行了比较.
- 和摄入量,以及生长指标 (体重增加,头周长) 在生命的前28天和整个住院期间被评估.
主要成果:
- 与对照人群相比,患有骨质疏松症的婴儿在出生后的前4周平均每周和摄入量显著降低.
- 骨质疏松症组的平均每日体重增加较低 (19.03克 vs 21.45克),头周长增长较小 (0.57厘米 vs 0.68厘米).
- 统计分析证实病例和对照组之间营养摄入量和生长参数的显著差异 (p<0.05).
结论:
- 较低的和摄入量与骨质疏松症和VLBW早产婴儿的生长受损有关.
- 及时和足够的和补充是预防骨质疏松症的必要条件.
- 优化营养供应对于促进VLBW婴儿的最佳骨生长和整体发育至关重要.
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