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Updated: Jan 16, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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Published on: July 12, 2012

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表观基因组和转录基因组衰老的可塑性揭示了通过环境暴露重新编程的共同目标

Cheryl Walker1, Sandra Grimm1, Rahul Jangid1

  • 1Baylor College of Medicine.

Research square
|September 26, 2025
PubMed
概括

早期接触有毒物质会重编程表观基因组,改变肝脏衰老的基因表达,并导致肝脏疾病的发生. 这种重新编程会产生持久的细胞变化,反映人类肝脏疾病和癌症.

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