信任评级对抑郁症感知决策的反应性降低的影响
Luoya Zhang1,2, Yelu Liu1,2, Yuxiang Wang1,2
1Department of Psychiatry, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Frontiers in neuroscience
|September 26, 2025
概括
重度抑郁症 (MDD) 损害了元认知反应能力,影响了信心评级和决策. 与健康对照组相比,患有MDD的患者在准确性改善和证据积累方面表现出缺陷.
科学领域:
- 认知神经科学 认知神经科学
- 临床心理学 临床心理学
- 精神病学是一个精神病学.
背景情况:
- 追溯信心评级 (CRs) 影响决策,延长响应时间 (RTs) 和提高准确性,这种现象被称为反应效应.
- 这种效应与元认知控制过程有关,但其通过抑郁病理,特别是严重抑郁症 (MDD) 的修改仍然未得到充分研究.
研究的目的:
- 调查MDD患者和健康对照 (HCs) 之间的反应效应的差异.
- 探索信任监测对抑郁症决策过程的影响.
主要方法:
- 对94名MDD患者和97名HC患者进行了感知决策任务.
- 使用漂移扩散模型 (DDM) 分析来分析响应时间和决策准确性.
主要成果:
- 促成的CRs在两组中都延长了RTs,但仅在HC中提高了决策准确性,而在MDD组中没有这种效果.
- 在CR条件下,DDM分析显示,在两组中,决策值都增加了.
- 一个显著的相互作用表明,与MDD患者相比,HCs增强了证据积累速度 (漂移率).
结论:
- 在MDD中,元认知反应效应受损,特别是在信任监测中.
- 抑郁症与超认知监测和控制过程的缺陷有关,这会影响决策的准确性和速度.
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