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Updated: Jan 16, 2026

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
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引入硫化物作为减轻聚乙烯甘抗原性在纳米医学中负荷中性术语

Dulce M Sánchez-Cerrillo1, Kouichi Shiraishi2, Lucía Mallen-Huertas1

  • 1Systems Chemistry Department, Institute for Molecules and Materials, Radboud University Nijmegen, Heyendaalseweg 135, Nijmegen 6525 AJ, The Netherlands.

JACS Au
|September 26, 2025
PubMed
概括

新的ylide-PEG (yPEG) 修改减少了抗PEG抗体的识别,提高了纳米医药的性能. 这一策略增强了聚合物的水友性和隐形性质,为生物材料和涂料提供了一种新的方法.

关键词:
通过PEGylation进行化.抗体识别 抗体识别纳米医药是一种纳米医药.硫化物抗原性 抗原性

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相关概念视频

Preparation and Reactions of Sulfides02:26

Preparation and Reactions of Sulfides

Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
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