非结核性喉颗粒瘤:系统审查和病例系列
Seraphina Key1, Michael Fook-Ho Lee1,2, William Jiang3
1Faculty of Medicine and Health, University of Sydney, Camperdown, New South Wales, Australia.
ANZ journal of surgery
|September 26, 2025
概括
诊断喉颗粒瘤需要高度怀疑自身免疫和传染病因. 这项研究回顾了这些具有挑战性的粘膜下病变的诊断途径.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 病理学 病理学 病理学
- 传染性疾病 传染性疾病
背景情况:
- 粘膜下喉病变可以模仿瘤,导致诊断挑战.
- 虽然Mycobacterium结核病是常见的原因,但非结核性颗粒瘤有不同的病因.
- 为了澄清诊断过程,进行了系统审查和病例系列.
研究的目的:
- 为了阐明下粘膜下喉颗粒瘤的诊断过程.
- 为了确定各种传染性和自身免疫病因的喉颗粒瘤.
- 在喉活检中提出颗粒状疾病的诊断途径.
主要方法:
- 对MeSH术语"粒瘤"和"喉"进行系统审查.
- 包括关于非恶性,非自身免疫,非传染性喉颗粒性疾病的研究.
- 使用JBI和ROBIN-I工具回顾案例系列数据收集和偏差风险评估.
主要成果:
- 包含了30名患者的9篇论文,详细介绍了传染病因,如莱什曼病和细胞质体病.
- Sarcoidosis 被提出为一种自身免疫性原因.
- 复制活检和开放活检有时对于非诊断性的微喉镜病例是必要的.
结论:
- 怀疑的高指数对于管理自身免疫和传染性喉颗粒瘤至关重要.
- 目前的自身免疫检测是非特异性的,可能需要重复活检.
- 国际合作可以促进喉粒状活组织检查的标准化诊断途径.
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