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Updated: Jan 16, 2026

Validation of a Mouse Model to Disrupt LINC Complexes in a Cell-specific Manner
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Published on: December 10, 2015

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通过2B拓酶和B层受体对基因组-核层相互作用的协调控制

Tom van Schaik1,2, Mikhail Magnitov1, Marcel de Haas1,2,3

  • 1Division of Gene Regulation, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

Nucleic acids research
|September 26, 2025
PubMed
概括

DNA拓酶2β (TOP2B) 保护特定的基因组区域免受核膜的影响. 它与层状B受体 (LBR) 的协调作用维持基因组组织,防止在瘤基因诱导的衰老中看到的变化.

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