monarchr:一个用于查询生物医学知识图的R包
Shawn T O'Neil1, Brian M Schilder2, Kevin Schaper1
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Bioinformatics (Oxford, England)
|September 26, 2025
概括
研究人员现在可以使用R编程语言查询和操纵生物医学知识图 (KG),使用新的monarchr包. 该工具简化了对复杂生物数据的访问,增强了研究能力.
科学领域:
- 生物信息学是一种生物信息学.
- 计算生物学 计算生物学
- 基因组学就是基因组学.
背景情况:
- 生物医学知识图 (KGs) 整合了大量的生物数据,包括基因,变异,疾病和表型.
- 在R编程语言中访问和操作KG数据的现有工具是有限的.
研究的目的:
- 介绍monarchr,一个用于查询和操纵生物医学KG数据的R包.
- 为R用户提供了与KG工作的增强功能,包括君主倡议KG和KGX格式中的任何KG.
主要方法:
- 开发了monarchr R软件包,其界面采用了整洁的灵感.
- 实施对君主倡议 (KG) 的支持.
- 适应任何符合知识图交换 (KGX) 格式的KG.
主要成果:
- monarchr为KG数据分析提供了一个直观和代的方法.
- 该软件包可以在R环境中无查询和可视化复杂的生物医学数据.
结论:
- monarchr解决了在R中使用KG的工作局限性,为研究人员提供了一个强大的新工具.
- 该软件包可更轻松地访问和处理生物医学KG数据,支持广泛的研究应用.
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