冷压器测试的稳定性:在不同地理位置研究疼痛感知和耐受性
Maria Belen Garay1, Rasmus Hagn-Meincke2,3, Lili Fekete4
1Servicio de Aparato Digestivo, Hospital General Universitario Dr. Balmis, Alicante, Spain.
Scandinavian journal of pain
|September 26, 2025
概括
冷压器测试显示了基于种族和手部暴露面积的疼痛耐受性的差异. 然而,关于预期疼痛的说明并没有改变测试结果,证实了它在疼痛研究中的可靠性.
科学领域:
- 疼痛研究 疼痛研究
- 人类生理学 人类生理学
- 心理物理学的精神物理.
背景情况:
- 冷压器测试 (CPT) 是一种广泛使用的,低成本的方法,用于疼痛研究,以诱导疼痛和不愉快感.
- 现有的研究缺乏关于种族,肢体暴露区域和教学线索如何影响CPT结果的全面数据.
研究的目的:
- 调查种族 (亚洲人与欧洲人) 在CPT期间对疼痛耐受性的影响.
- 检查手部浸泡的不同区域 (两个手指,四个手指,整个手) 如何影响疼痛感知和耐受性.
- 确定指导与非指导疼痛预期对CPT结果的影响.
主要方法:
- 一个混合的亚洲和欧洲健康人群参与了两个随机试验.
- 试验1 (n=54) 使用交叉设计来评估不同手部浸泡程度的疼痛耐受性.
- 试验2 (n=40) 使用横截面设计来比较指导与非指导的疼痛预期.
主要成果:
- 与亚洲人 (93 ± 36 秒; p < 0.001) 相比,欧洲人表现出明显更长的疼痛耐受性 (116 ± 14 秒).
- 在欧洲组中,较少的受试者提前撤回了他们的手 (9%对43%;p = 0.007).
- 疼痛耐受性受到刺激区域 (p < 0.001) 的显著影响,双指浸泡比全手浸泡更能耐受. 疼痛预期指令没有显著影响疼痛评级 (p = 0.88) 或耐受性 (p = 1).
结论:
- 冷压机测试证明了跨性别,种族和不同教学水平的稳定性.
- 根据刺激的位置和强度,观察到疼痛感知和耐受性的显著变化.
- CPT的可靠性得到了进一步的支持,发现疼痛预期指令不会改变结果.
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