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mRNA多-HLAII类 黑色素瘤的免疫疗法

Apostolos P Georgopoulos1,2,3, Lisa M James1,2,4, Matthew Sanders1,2,3

  • 1The HLA Cancer Research Group, Brain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis VAMC, One Veterans Drive, Minneapolis, MN 55417, USA.

Cells
|September 26, 2025
PubMed
概括

研究人员从结合人类白细胞抗原II类分子的黑色素瘤蛋白中鉴定出679个高抗原性表位. 这些-HLAII类复合物显示出开发新型癌症疫苗和治疗方法的前景.

关键词:
主要组织相容性复合体 (MHC)癌症 癌症 癌症 癌症 癌症人类白细胞抗原 (HLA)免疫疗法 免疫疗法黑色素瘤是一种黑色素瘤.新抗原是一种新抗原.

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