相关实验视频
Updated: Jan 16, 2026

12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
19.3K
瘤药物短缺及其对社区医院的影响
Lyndsey Reich1, Kevin B Knopf1,2,3
1Sutter Health Care Department of Internal Medicine, Oakland, CA.
Cancer journal (Sudbury, Mass.)
|September 26, 2025
概括
瘤药物短缺,特别是类药物短缺,不成比例地影响社区医院服务于弱势群体. 创造性解决方案和系统性改革对于公平获得癌症护理和供应链弹性至关重要.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 药品供应链管理 药品供应链管理
背景情况:
- 持续存在的基本瘤药物短缺,特别是诸如白金剂之类的通用化疗,严重影响了医疗保健的提供.
- 社区和安全网医院经常为农村和服务不足的人口提供服务,由于有限的财政资源,他们面临着更大的挑战.
- 药品灰色和黑色市场的出现引发了对药品质量和患者安全的严重担忧,特别是在低收入和中等收入国家.
研究的目的:
- 检查瘤药物短缺对社区医院的实际影响.
- 突出一个面临药物短缺的社区医院所采用的创造性资源最大化策略.
- 讨论更广泛的市场动态和政策变化,加剧癌症护理差异.
主要方法:
- 对社区医院对药物短缺的反应进行案例研究分析.
- 检查市场动态,包括价格和医疗保健政策.
- 审查安全网机构和服务不足的人群所面临的挑战.
主要成果:
- 在缺乏期间,社区医院实施了创造性的解决方案来管理有限的药物资源.
- 灰色和黑色市场正在出现,对药品质量构成风险,特别是在资源有限的环境中.
- 金价格上和政策转变可能会加剧癌症护理获取现有的差距.
结论:
- 迫切需要进行系统性改革,以提高药物供应链对瘤药物的弹性.
- 确保平等获得必要的癌症药物对于弱势机构和患者群体至关重要.
- 解决市场动态和政策影响是必要的,以减轻癌症护理领域日益加深的差异.
相关概念视频
Cancer Therapies
9.8K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
9.8K
Issues And Trends In Healthcare Delivery System
6.1K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.1K
Treatment Resistant Cancers
3.7K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.7K
Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow
214
Chronic liver disease significantly impacts drug metabolism due to alterations in hepatic blood flow and enzyme accessibility. This disruption affects the body's pharmacokinetics—the movement and processing of drugs within the system. Key enzymes crucial for metabolizing medications become less accessible, changing how drugs are processed and utilized. Furthermore, liver disease influences the synthesis of plasma proteins, such as albumin and globulins, which play critical roles in drug...
214
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
256
Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...
256
Factors Affecting Drug Distribution: Miscellaneous Factors
947
Drug distribution in the human body is a complex process influenced by various individual factors, including age, pregnancy, obesity, diet, body water composition, pH levels, and specific disease conditions.
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...
947

