伊贡圣提取物调节新陈代谢,抗氧化状态和免疫功能,改善腹小牛的健康状况
Sijuan Huang1,2,3, Chao Han1,2,3, Jianyu Lv1,2,3
1State Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
益功圣 (YGS) 通过提高抗氧化能力和减少炎症,有效治疗小牛腹. 这种传统的中医药提供了一个有前途的抗生素替代品,以改善奶牛养殖中的小牛的健康.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 药理学 药理学是指药理学的学科.
- 传统中国医药 传统中国医药
背景情况:
- 小牛腹显著影响乳制品生产,经常用抗生素治疗,引发了对残留物和耐药性的担忧.
- 在小牛保健中,急需安全有效的抗生素替代品.
- 传统中医药Yigong San (YGS) 适用于胃肠道炎症.
研究的目的:
- 评估Yigong San (YGS) 作为治疗小牛腹的潜在抗生素替代品.
- 调查YGS在缓解小牛腹的潜在机制.
主要方法:
- 20只腹的小牛被用YGS治疗了7天,与对照组和自然腹的小组一起.
- 血清样本分析了生物化学参数,氧化应激标志物,细胞因子和代谢概况.
主要成果:
- YGS治疗改善了生化指标和增强了抗氧化能力 (增加了CAT,GSH-PX,SOD;减少了MDA).
- YGS显著降低了促炎性细胞因子 (IL-1α,TNF-α,IL-1β,IL-17A,IL-18,IL-21,IFN-γ) 和化学因子 (CXCL9,CXCL10).
- 代谢分析显示,YGS改善了代谢障碍,丰富了氨酸和氨酸代谢途径,特定的代谢物与炎症负相关.
结论:
- 通过提高抗氧化能力,减少炎症,调节免疫功能和代谢物,YGS有效治疗小牛腹.
- 在奶牛养殖中,YGS为牛犊腹管理提供了抗生素的有价值,安全和有效的替代品.
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