牙周病学精确性范式:为定制诊断,治疗和预防提供一个多层次的框架
Gianna Dipalma1,2, Angelo Michele Inchingolo1,2, Francesco Inchingolo1
1Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.
Journal of personalized medicine
|September 26, 2025
概括
精密牙周病学定制了使用个体患者数据的预防,诊断和治疗. 与标准方法相比,这种个性化的方法可以改善结果并减少牙损失.
科学领域:
- 牙周病学 牙周病学
- 精准医学是一门精准的医学.
- 基因组学就是基因组学.
背景情况:
- 标准化的牙周治疗方法往往忽略了疾病风险和进展的患者特异性变化.
- 精准医学旨在根据生物学,遗传,行为和环境因素来定制护理.
研究的目的:
- 系统地审查目前关于精准医学在牙周病学中的应用的证据.
- 评估个性化方法对牙周病的诊断,治疗和预防的影响.
主要方法:
- 根据PRISMA指南进行了系统审查.
- 在2014-2025年期间,主要数据库 (PubMed,Scopus,Web of Science) 进行了搜索.
- 包括16项研究,并使用ROBINS工具评估偏差风险.
主要成果:
- 综合生物标志物和数字平台的诊断工具提高了准确性和早期检测.
- 个性化治疗,包括宿主调节疗法和定制抗生素,改善了临床结果.
- 基于风险分析的定制预防策略减少了牙损失和优化了护理频率.
结论:
- 精密牙周科整合了omics技术,实时诊断和行为洞察力,以实现以患者为中心的护理.
- 这种范式转变提高了诊断精度,治疗疗效和长期疾病预防.
- 这些发现支持在临床实践中更广泛地实施精密牙周病理学.
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